Could the key to understanding autism lie in the gut? A groundbreaking study suggests that a mother’s microbiome—the collection of bacteria in her digestive system—might influence her child’s risk of developing autism.
The research, published in The Journal of Immunology, focused on a molecule called IL-17a, produced by the immune system. In mice, high levels of this molecule were linked to autism-like behaviors in offspring. When scientists blocked IL-17a during pregnancy, the pups developed normally. But when the molecule was allowed to function, the mice exhibited social and repetitive behaviors associated with autism.
To confirm the role of gut bacteria, researchers transplanted microbes from one group of mice to another. The result? The second group’s offspring also showed signs of the disorder.
Though more research is needed, the study highlights a fascinating connection between gut health and brain development. Scientists now hope to pinpoint the exact bacteria involved and explore whether similar patterns exist in humans.
